Figure 4.

OrtT reduces cellular metabolism under THF-related antimicrobial stress. (A) Metabolic activity of the wild-type, ∆ortT ∆Kan, and ∆ghoT ∆Kan strains in response to 3 µg/mL carbenicillin or water (negative control); (B) Metabolic activity of the wild-type, ∆ortT ∆Kan, and ∆ghoT ∆Kan strains in response to 1 µg/mL TMP or DMSO (negative control); (C) Metabolic activity of the wild-type strain and ∆ortT ∆Kan in response to 60 µg/mL SMZ or DMSO (negative control). Two independent cultures were evaluated for each experiment. Error bar represents standard deviation.