Table 1.
Comparison of median lethal doses (LD50) of four sea snake venoms via different routes of administration into mice.
| Venom | LD50 i.v. (µg/g) | LD50 i.m. (µg/g) | LD50 s.c. (µg/g) |
|---|---|---|---|
| Hydrophis schistosus (Malaysia) | 0.07 (0.05–0.09) | 0.10 (0.08–0.12) | 0.09 (0.06–0.14) |
| Hydrophis curtus (Malaysia) | 0.11 (0.07–0.17) | 0.18 (0.12–0.27) | 0.18 (0.17–0.18) |
| Laticauda laticaudata | 0.10 (0.08–0.12) | - | - |
| Laticauda semifasciata | 0.22 (0.15–0.34) | - | - |
i.v.: intravenous; i.m.: intramuscular; s.c.: subcutaneous; -: not determined. Units expressed as µg reconstituted venom per g mouse body weight.