Table 2.
Univariate and multivariate logistic regression analyses for the association between microalbuminuria and various variables in hypertensive patients.
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| Odds Ratio (95% CI) | p | Model 1(BMI) | Model 2(WC) | |||
| Odds Ratio (95% CI) | p | Odds Ratio (95% CI) | p | |||
| Gender, male | 0.85 (0.60–1.21) | 0.375 | — | — | — | — |
| Age, years | 1.21 (1.01–1.04) | 0.001 | 1.03 (1.01–1.05) | 0.005 | 1.03 (1.02–1.05) | 0.007 |
| Physical activity | 0.94 (0.67–1.33) | 0.741 | — | — | — | — |
| Smoke statues | 0.95 (0.72–1.24) | 0.687 | — | — | — | — |
| Alcohol use | 0.95 (0.77–1.19) | 0.67 | — | — | — | — |
| BMI, kg/m2 | 1.07 (1.02–1.12) | 0.004 | 1.10 (1.04–1.16) | <0.001 | — | — |
| WC, cm | 1.03 (1.01–1.05) | 0.008 | — | — | — | — |
| SBP, mmHg | 1.02 (1.01–1.03) | <0.001 | 1.02 (1.01–1.04) | <0.001 | 1.02 (1.01–1.03) | <0.001 |
| DBP, mmHg | 1.01 (0.99–1.02) | 0.451 | — | — | — | — |
| Fasting glucose, mmo/L | 1.28 (1.17–1.40) | <0.001 | 1.27 (1.15–1.39) | <0.001 | 1.29 (1.18–1.42) | <0.001 |
| Insulin, nU/L | 1.02 (1.00–1.04) | 0.021 | — | — | — | — |
| Serum creatinine, umol/L | 1.00 (0.99–1.01) | 0.494 | — | — | — | — |
| UA, umol/L | 1.00 (0.99–1.00) | 0.866 | — | — | — | — |
| hs-CRP, mg/L | 1.04 (1.00–1.07) | 0.029 | — | — | — | — |
| TG, mmol/L | 1.08 (0.95–1.22) | 0.225 | — | — | — | — |
| LDL-C, mmol/L | 0.96 (0.80–1.16) | 0.698 | — | — | — | — |
| HDL-C,mmol/L | 0.98 (0.58–1.64) | 0.926 | — | — | — | — |
Independent variables in the multivariate model were chosen using a backward stepwise regression analysis where all variables listed in the univariate analysis. BMI and WC were selected into model 1 and model 2 separately. Serum insulin was excluded from the multivariate model due to possible multicollinearity. The goodness-of-fit of the logistic regression models was assessed by the Hosmer and Lemeshow test, and the p value was 0.525, and 0.277 for model 1 and model 2, respectively. Abbreviations: ACR, albumin to creatinine ratio; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; UA, uric acid ; hs-CRP, high sensitivity C-reactive protein; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.