Table 1.
Baseline characteristics of the study population a
| Parameter | Total cohort ( N = 5,056) | Sepsis subgroup ( n = 1,832) | |
|---|---|---|---|
| Age, yr | 65 (51 to 78) | 69 (55 to 80) | |
| Female sex, n (%) | 2,377 (47) | 879 (48) | |
| Care unit, n (%) | |||
| Cardiac intensive care unit | 1,264 (25) | 384 (21) | |
| Cardiac surgical intensive care unit | 1,154 (23) | 427 (23) | |
| Medical intensive care unit | 2,361 (47) | 979 (53) | |
| Surgical intensive care unit | 227 (6) | 42 (2) | |
| Comorbid conditions, n (%) | |||
| Congestive heart failure | 1,254 (25) | 651 (36) | |
| Chronic obstructive pulmonary disease | 953 (19) | 343 (19) | |
| Diabetes | 1,167 (23) | 474 (26) | |
| Hypertension | 1,518 (30) | 499 (27) | |
| Mechanical ventilation (first 24 hr), n (%) | 2,343 (46) | 934 (51) | |
| Vasopressor use (first 24 hr), n (%) | 1,397 (28) | 756 (41) | |
| Glasgow Coma Scale score (IQR) | 14 (8 to 15) | 14 (8 to 15) | |
| Simplified Acute Physiology Score I (IQR) | 14 (10 to 18) | 16 (12 to 20) | |
| Sequential Organ Failure Assessment score (IQR) | 6 (3 to 9) | 8 (4 to 11) | |
aData are median and interquartile range (IQR) or number and percentage.