Table 2.
Characteristics of studies included in the meta-analysis
| First author (Year) | Country | Ethnicity | Sample size (case/control) | Genotyping methods | Matching criteria | Source of control | GC ascertainment | Quality scores | HWE ( P value) |
|---|---|---|---|---|---|---|---|---|---|
| Hamai 2004 | Japan | Asian | 200/230 | PCR-RFLP | Age, sex, and H. pylori infection | HB | NR | 5.5 | 0.647 |
| Goto 2005 | Japan | Asian | 202/450 | PCR-CTPP | NR | PB | Pathologically confirmed | 6.5 | 0.537 |
| Jin 2007 | China | Asian | 617/660 | PCR-RFLP | Age, sex, smoking and drinking | PB | Histopathologically confirmed | 7.0 | 0.407 |
| Araujo 2011 | Portugal | Caucasian | 207/984 | PCR-RFLP | NR | HB | Histologically confirmed | 4.5 | 0.010 |
| Yang 2012 | China | Asian | 207/318 | PCR-RFLP | Age, and sex | HB | Histologically confirmed | 6.5 | 0.272 |
| Lin 2012 | China | Asian | 114/120 | PCR-RFLP | Sex | HB | Pathologically confirmed | 5.0 | 0.485 |
GC, Gastric cancer; NR, Not reported; PB, Population–based; HB, Hospital–based; HWE, Hardy–Weinberg equilibrium in control population; PCR–RFLP, Polymerase chain reaction-restriction fragment length polymorphism; PCR-CTPP, PCR with confronting two-pair primers; H. pylori, Helicobacter pylori.