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Acidosis. Development of acidosis, measured by base excess after 0, 6, 12, 18 and 24 hours in septic and sham-operated rats. Animals were under continuous sedation with propofol, isoflurane, sevoflurane or desflurane and under continuous mechanical ventilation. Values represent mean ± standard deviation. *P <0.05 versus isoflurane + CLP. CLP, cecal ligation and puncture.
