Table 1.
Characteristics of breast cancer cell lines
| Cell line a | Transformed | Molecular subtype | Histological pathology b | ER expressed | PR expressed | Her2 amplified |
|---|---|---|---|---|---|---|
| MCF-10A | No | Basal | Fibrocystic | No | No | No |
| MCF-12A | No | Basal | Fibrocystic | No | No | No |
| BT-474 | Yes | Luminal B | DC | Yes | Yes | Yes |
| MCF-7 | Yes | Luminal A | AC | Yes | Yes | No |
| MCF-7LTamR | Yes | Luminal A | AC | Yes | Yes | No |
| MDA-MB-231 | Yes | Basal | AC | No | No | No |
| MDA-MB-468 | Yes | Basal | AC | No | No | No |
| SUM-149 | Yes | Basal | IBC | No | No | No |
| SUM-190 | Yes | Basal | IBC | No | No | Yes |
AC, adenocarcinoma; DC, ductal carcinoma; ER, estrogen receptor; IBC, inflammatory breast cancer; PR, progesterone receptor; Her2, human epidermal growth factor receptor 2. aMCF-10A and MCF-12A are spontaneously immortalized cells. bOriginal tissue or tumor.