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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Kidney Int. 2014 Oct 29;87(3):564–574. doi: 10.1038/ki.2014.346

Figure 1. Injection of mice with recombinant suPAR protein does not induce proteinuria.

Figure 1

A) A mouse suPAR ELISA standard curve was generated by adding indicated amounts of purified recombinant Fc-suPAR protein to serum from Plaur −/− mice diluted 1:4. B) Serum suPAR concentration concentration at indicated time points following injection of purified recombinant suPAR protein was estimated using ELISA. Experimental mice (n=5) injected with recombinant protein (solid line) were compared to control mice (n=4) injected with PBS (dashed line). C) Urine albumin and creatinine ratios were calculated at 12 h and 24 h post-Fc-suPAR injection; control (white columns), experimental (gray columns) group. All values are expressed as mean ± standard error of the mean. ** p <0.01, * p <0.05, comparing experimental to control groups at each time point.