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. Author manuscript; available in PMC: 2016 Mar 19.
Published in final edited form as: Neuroscience. 2015 Jan 14;289:289–299. doi: 10.1016/j.neuroscience.2015.01.003

Figure 1. Glial activation is detectable early in Sca1154Q/2Q mice.

Figure 1

Cerebellar sections from 8 and 12 weeks old Sca1154Q/2Q mice and wild-type littermates were stained with GFAP, S100β and Iba1 antibodies. a and d Representative images of GFAP (a) and S100β (d) staining in cerebellar cortex. b, c and e Intensity of GFAP (a and c, N = 4) and S100β (e, N = 4) staining f Number of Iba1 positive (Iba1+) cells ( N= 5) in the cerebellar cortex. Student's t-test P values are shown with all the histograms. Error bars represent SEM. Scale bar = 90 μm