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. Author manuscript; available in PMC: 2016 Mar 19.
Published in final edited form as: Neuroscience. 2015 Jan 14;289:289–299. doi: 10.1016/j.neuroscience.2015.01.003

Figure 3. Glial activation occurs early in transgenic ATXN1[82Q] mice before behavioral and cerebellar tissue pathology.

Figure 3

Cerebellar sections from four weeks old ATXN1[82Q] and wild-type littermates mice were stained with GFAP and Iba1 antibodies. a and c Representative images of GFAP (a) and Iba1 (c) staining in cerebellar cortex. b and e Intensity of GFAP staining in 4 week old mice (b, N = 7); e time course; d and f Number of Iba1 + cells (4 week old mice; N=5) f time course. Student's t-test P values are shown with all the histograms. Error bars represent SEM. Scale bar = 45 μm