Table 4. Integrated Discrimination Index and Category Free Net Reclassification Index for Individual Biomarkers in Persistent Doubling of Creatinine Model.
| uNGAL | uL-FABP | uIL-18 | uKIM-1 | |
|---|---|---|---|---|
| IDI | ||||
| Events to higher risk | 0.0099 | 0.0680 | 0.0095 | 0.0111 |
| Non-Events to lower risk | 0.0031 | 0.0211 | 0.0030 | 0.0034 |
| Total | 0.0129 | 0.0891 | 0.0125 | 0.0145 |
| (95% CI) | (-0.0052-0.0310) | (0.0336-0.1445) | (-0.0118-0.0367) | (-0.0052-0.0343) |
| NRI | ||||
| %Events to higher risk | 66.7 | 55.6 | 58.3 | 63.9 |
| %Events to lower risk | 33.3 | 44.4 | 41.7 | 36.1 |
| %Non-Events to higher risk | 47.4 | 34.5 | 43.1 | 43.1 |
| %Non-Events to lower risk | 52.6 | 65.5 | 56.9 | 56.9 |
| Total NRI for events | 33.3 | 11.1 | 16.7 | 27.8 |
| (95% CI) | (0.7-66.0) | (-21.6-43.8) | (-16.0-49.3) | (-4.9-60.4) |
| Total NRI for non-events | 5.2 | 31.0 | 13.8 | 13.8 |
| (95% CI) | (-13.0-23.4) | (12.8-49.2) | (-4.4-32.0) | (-4.4-32.0) |
| Total cfNRI | 38.5 | 42.1 | 30.5 | 41.6 |
| (95% CI) | (1.1-75.9) | (4.8-79.5) | (-6.9-67.9) | (4.2-79.0) |