Table 2.

Insulin resistance indices and markers of cardiovascular risk in obese adolescents with normal and abnormal LV structure

	Control subjects	Obese subjects		P value	P value
	Lean (n=14)	Normal (n=34)	Abnormal (n=10)	Control subjects vs. Obese subjects	Obese subjects Normal vs. Abnormal
Insulin resistance indices
Fasting Insulin, mL/uU	8.3 (2.70–14.80)	15.65 (5.00–26.00)	16.50 (3.50–24.00)	0.004	0.79
HOMA-IR, Umol	1.8 (0.57–2.66)	3.45 (1.01–5.13)	3.46 (0.67–5.08)	0.007	0.66
Markers of cardiovascular risk
BMI Z-score	−0.115(−0.46-0.145)	2.24 (1.78–2.38)	2.35 (1.61–2.65)	<0.001	0.28
Systolic blood pressure (mm/Hg)	109.00 (98.00-120.00)	115.50 (100.00–122.00)	109.50 (101.00–116.50)	0.03	0.35
Diastolic blood pressure (mm/Hg)	68 (57.00 -76.00)	66.00 (60.00–72.00)	69.00 (55.50–77.00)	0.49	0.59
Fasting glucose, mg/dL	88.80 (81.00–98.00)	86.00 (77.90–90.00)	82.50 (75.50–80.00)	0.34	0.49
Total cholesterol, mg/dL	126.70 (92–176.00)	212.00 (146.20–238.00)	185.50 (157.00–208.00)	<0.001	0.46
Triglycerides, mg/dL	64 (30.00–160.00)	170.50 (90.80–236.00)	131.50 (77.00–281.00)	<0.001	0.78
LDL cholesterol, mg/dL	69 (53.00 - 110.00)	126.00 (67.00–155.50)	120.00(59.50 - 133.00)	<0.001	0.21
HDL cholesterol, mg/dL	44.70 (31.00–60.00)	42.00 (26.90–48.00)	36.50 (33.00–39.00)	0.39	0.41

Values are median (25 ^th– 75 ^th percentile).

Normal, Normal LV structure; Abnormal, Abnormal LV structure