Skip to main content
. Author manuscript; available in PMC: 2016 Feb 27.
Published in final edited form as: Circ Res. 2015 Jan 13;116(5):857–866. doi: 10.1161/CIRCRESAHA.116.305629

Figure 5. Exogeneous BMP7 ameliorates experimental EFE.

Figure 5

(A) Representative photomicrographs of Masson’s Trichrome–stained sections from rat hearts two weeks after heterotopic transplantation without (left) and after rhBMP7 treatment (right) and (B) Quantification of fibrotic and cardiomyocyte area in control and rhBMP7 treated hearts. (C, D) Measurement of the EFE area of slices located from the base to the apex of rat hearts from the left ventricle and the valvular endocardium after heterotopic transplantation. The left picture shows the anatomic position of the slices. The Graph shows the measurement of the mean EFE area in mm2. Each data point reflects at least six measured slices. Data series of slices from hearts without rhBMP7 treatment are highlighted in red; those from slices of hearts after rhBMP7 treatment are highlighted in green. (*p<0.05).