Table 3.
Evaluation of the impact of comorbidity load and hypothesized predictors on IWQOL-Kids scores for Teen-LABS participants by sex.
| FEMALES | Total | Physical Comfort | Body Esteem | Social Life | Family Relationsa | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| β (95% CI) | P Value | β (95% CI) | P Value | β (95% CI) | P Value | β (95% CI) | P Value | β (95% CI) | P Value | |
| CLoad | −1.32 (−2.70, 0.06) | 0.06 | −1.46 (−3.46, 0.55) | 0.15 | −1.08 (−3.11, 0.95) | 0.30 | −1.81 (−3.72, 0.10) | 0.06 | −0.04 (−0.07, −0.01) | 0.01 |
| BMI | −0.30 (−0.60, −0.01) | 0.04 | −1.03 (−1.43, −0.63) | < 0.01 | b | b | b | |||
| White race | −5.98 (−11.21, −0.75) | 0.03 | b | −10.37 (−18.65, −2.09) | 0.01 | b | b | |||
| DEPc | −15.11 (−21.53, −8.68) | < 0.01 | −10.34 (−19.64, −1.03) | 0.03 | −23.76 (−34.19, −13.13) | <0.01 | −12.44 (−21.81, −3.07) | <0.01 | −0.20 (−0.33, −0.08) | <0.01 |
| BED | −10.00 (−16.43, −3.56) | <0.01 | −14.83 (−24.24, −5.41) | <0.01 | −10.84 (−21.18, −0.51) | 0.04 | −10.25 (−19.59, −0.91) | 0.03 | b | |
| PAIN | b | b | b | b | b | |||||
| GERD | b | b | b | b | −0.15 (−0.29, −0.01) | 0.03 | ||||
| OSA | b | b | b | b | b | |||||
| Pseudo-R2 | 0.27 | 0.24 | 0.21 | 0.11 | 0.08 | |||||
| MALES | ||||||||||
| CLoad | −4.30 (−7.04, −1.56) | <0.01 | −5.47 (−8.82, −2.12) | <0.01 | −3.28 (−7.51, 0.95) | 0.13 | −4.82 (−9.00, −0.65) | 0.02 | −0.02 (−0.04, −0.004) | 0.02 |
| BMI | b | −0.93 (−1.42, −0.45) | <0.01 | b | b | b | ||||
| White race | b | b | b | b | b | |||||
| DEPc | −21.69 (−38.98, −4.40) | 0.01 | b | −31.44 (−37.90, −23.09) | 0.02 | −30.54 (−56.85, −4.22) | 0.02 | b | ||
| BED | b | b | b | b | b | |||||
| PAIN | b | −9.84 (−20.24, 0.56) | 0.06 | b | b | b | ||||
| GERD | b | b | b | b | b | |||||
| OSA | b | b | b | b | b | |||||
| Pseudo-R2 | 0.28 | 0.50 | 0.16 | 0.21 | 0.09 | |||||
BED= Binge Eating Disorder; BMI= Body Mass Index; CLoad= Comorbidity Index; DEP= Depression; GERD = Gastroesophageal Reflux Disorder; OSA= Obstructive Sleep Apnea; PAIN = Joint or Back Pain.
All listed variables were considered for inclusion in the models. Multivariable mixed-effect linear regression models, with clinical site as a random effect, were completed with imputed datasets (M=25) for females and males. P values are for those variables retained in the final model. Pseudo-R2 values refer to the proportion of the variance in the outcome explained by the set of predictor variables.
Log transformed.
Not included in final model.
Clinical range based on the Beck Depression Inventory-II total raw score ≥ 17.