Table VI.
Asthma symptoms, lung function and sinus symptoms in adults (ages 18 and older) treated with mometasone versus placebo.
Treatment Assignment | Rate Ratio (95% CI)* Mometasome / Placebo |
P-value* | ||
---|---|---|---|---|
Mometasone (N = 111) |
Placebo (N = 111) |
|||
| ||||
Episodes of poor asthma control, overall | ||||
Patients with ≥ 1 event, N (%) | 45 (41%) | 48 (43%) | ||
Number of events | 104 | 114 | ||
Annual per-person event rate (95% CI) | 2.5 (1.9, 3.5) | 2.6 (1.9, 3.5) | 0.98 (0.64, 1.51) | 0.92 |
Episodes of poor asthma control, components | ||||
Drop in peak flow of ≥ 30 % for 2 consecutive days | ||||
Patients with ≥ 1 event, N (%) | 14 (21%) | 20 (27%) | ||
Number of events | 38 | 68 | ||
Annual per-person event rate (95% CI) | 0.9 (0.5, 1.5) | 1.7 (1.1, 2.6) | 0.55 (0.27, 1.10) | 0.09 |
Urgent asthma care | ||||
Patients with ≥ 1 event, N (%) | 6 (5%) | 11 (9%) | ||
Number of events | 6 | 14 | ||
Annual per-person event rate (95% CI) | 0.1 (0.1, 0.3) | 0.3 (0.2, 0.6) | 0.45 (0.16, 1.27) | 0.13 |
Systemic steroids | ||||
Patients with ≥ 1 event, N (%) | 15 (14%) | 17 (15%) | ||
Number of events | 20 | 15 | ||
Annual per-person event rate (95% CI) | 0.3 (0.2, 0.5) | 0.4 (0.3, 0.7) | 0.78 (0.40, 1.52) | 0.47 |
Increased Rescue Medications | ||||
Patients with ≥ 1 event, N (%) | 29 (28%) | 27 (26%) | ||
Number of events | 62 | 49 | ||
Annual per-person event rate (95% CI) | 1.7 (1.1, 2.5) | 1.2 (0.8, 1.9) | 1.42 (0.78, 2.59) | 0.25 |
Rate Ratios, 95% Confidence Intervals (CIs) and p-values are based on negative binomial regression.