Table 5.

Multivariate Cox model analyses of prognostic factors of CRC in operated group

Variable	Hazard ratio	95%CI	P
Years of diagnosis			<0.001
1996-2000	1.000	Reference
2001-2005	0.944	0.930-0.959
Site			<0.001
Colon	1.000	Reference
Rectum	1.044	1.023-1.066
Age			<0.001
15-30	1.055	0.955-1.165	0.294
31-40	0.954	0.906-1.005	0.077
41-50	0.979	0.948-1.011	0.203
51-60	1.000	Reference
61-70	1.082	1.056-1.109	<0.001
71-80	1.325	1.294-1.356	<0.001
>80	1.951	1.902-2.002	<0.001
Pathological grading			<0.001
I- II	1.000	Reference
III-IV	1.443	1.418-1.468	<0.001
Unknown	0.913	0.880-0.948	<0.001
Histological Type			<0.001
Adenocarcinoma	1.000	Reference
Mucinous/Signet ring cancer	1.200	1.175-1.226
AJCC stage			<0.001
I- II	1.000	Reference
III- IV	4.880	4.791-4.971	<0.001
Unknown	1.170	1.130-1.210	<0.001
No. of LNs dissected			<0.001
<12	1.000	Reference
≥12	0.793	0.780-0.806	<0.001
Unknown	2.269	2.183-2.358	<0.001