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. 2015 Feb 25;15:82. doi: 10.1186/s12885-015-1065-8

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© Saito et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Rescue from lapatinib inhibition by FB-SN and abrogation by FGFR inhibitor. The inhibitory effect of lapatinib on the proliferation of representative cell lines is rescued by the addition of fibroblast culture supernatant. Further addition of FGFR inhibitor (PD-173074) abrogates the rescue effect of fibroblast supernatant. The Y axis indicates the absorbance.