Figure 2.
The c.890 A>G mutation decreases the rate of growth in transformed yeast strains. (A) Comparison of the sequences of human and yeast Coq2 proteins. The asterisk indicates the mutated Y>C residue. Conserved amino acids inside a frame. (B) Growth curves of the Δcoq2 yeast strain (squares), and of this strain transformed with: wild-type yCOQ2 (circles) or c.783 A>G mutated yCOQ2 (triangles). (C) Growth of the Δcoq2 yeast strain (squares) transformed with wild-type (circles) or mutant (triangles) hCOQ2.