Table 6.
Parameter estimates and 95% confidence intervals (CI) for adoption studiesa
Relationship | Study | Heritability estimate | 95% (CI) |
---|---|---|---|
Summary | All offspring | 0.356 | 0.216 to 0.499 |
Male offspring | 0.400 | 0.235 to 0.562 | |
Female offspring | 0.241 | −0.045 to 0.517 | |
Mother/son | Cloninger et al. (1981) | 0.166 | −0.100 to 0.738 |
Sigvardsson et al. (1996) | 0.210 | −0.062 to 0.865 | |
Father/son | Cloninger et al. (1981) | 0.172 | 0.092 to 0.588 |
Sigvardsson et al. (1996) | 0.181 | −0.005 to 0.711 | |
Parent/son | Cadoret et al. (1987) | 0.504 | 0.222 to 1.555 |
Goodwin et al. (1973) | 0.392 | −0.061 to 1.426 | |
Mother/daughter | Bohman et al. (1981) | 0.287 | 0.053 to 1.034 |
Sigvardsson et al. (1996) | −0.630 | −1.800 to 1.249 | |
Father/daughter | Bohman et al. (1981) | 0.062 | −0.276 to 0.513 |
Sigvardsson et al. (1996) | −0.031 | −0.889 to 0.736 | |
Parent/daughter | Goodwin et al. (1977) | 0.200 | −0.796 to 1.388 |
The heritability estimate for the adoption studies was estimated by doubling the correlation between the biological parents and offspring (in the same way that the genetic correlation between dizygotic twins is half the genetic correlation of monozygotic twins). Accordingly, the theoretical limits of the confidence intervals is −2 and 2 rather than −1 and 1.