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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Addict Biol. 2014 Aug 29;20(5):956–967. doi: 10.1111/adb.12180

Table 2.

Linear and Quadratic Rates of Change for ALC in Regional Volumes over 7.5 months of Abstinence

Region Linear Quadratic
β months abstinent SE p-value β months abstinent SE p-value
Frontal GM 1.68 0.28 < .001 −0.0048 0.0011 < .001
Parietal GM 0.95 0.17 < .001 −0.0030 0.0006 < .001
Temporal GM 0.49 0.26 .07 −0.0018 0.0010 .09
Occipital GM 0.30 0.10 .004 −0.0015 0.0004 .004
Total cortical GM 3.93 0.57 < .001 −0.0120 0.00007 < .001
Frontal WM 0.40 0.08 < .001 −0.0003 0.0011 .82
Parietal WM 0.20 0.04 < .001 0.0003 0.0003 .79
Temporal WM 0.13 0.03 < .001 −0.0006 0.0004 .17
Occipital WM 0.13 0.09 .13 −0.0006 0.0003 .06
Total lobar WM 0.75 0.14 < .001 0.0000 0.0017 .95
Cerebellum 0.93 0.13 < .001 −0.0027 0.0005 < .001
Thalamus 0.12 0.03 < .001 −.00033 0.00010 < .001
Lenticular nucleus −0.01 0.31 .15 .00003 0.00010 .91
Ventricular CSF −1.05 0.20 < .001 .00282 0.00070 < .001

Note. β = slope.

CSF: cerebrospinal fluid. GM: gray matter. SE: standard error of the estimate. WM: white matter.