Table 3.
Summary of studies utilizing DW-MRI to view cerebral ischemia and assessed global cognition using the MMSE.
| Study | n | Type of TAVI | Time after TAVI that DW-MRI was performed | Number of patients with lesions | Incidence of patients with lesions | Total number of lesions | Average number of lesions per patient |
|---|---|---|---|---|---|---|---|
| Ghanem et al., 2013 [6] | 111 | TF (MCV) = 95 TF (ES) = 16 |
3 days | 36a | 64% | — | — |
|
| |||||||
| Knipp et al., 2013 [10] | 27 | TA (ES) = 27 | 10.7 ± 4.9 days | 12 | 58% | 22 | 1.83 |
|
| |||||||
| Rodés-Cabau et al., 2011 [11] | 60 | TF (ES) = 29 TA (ES) = 31 |
4 ± 1 days | 19 22 |
66% 71% |
83 168 |
4.37 7.63 |
|
| |||||||
| Kahlert et al., 2010 [12] | 32 | TF (MCV) = 10 TF (ES) = 22 |
3.4 days (2.5–4.4) | 8 19 |
80% 86% |
26 89 |
3.25 4.68 |
n = number, TAVI = transcatheter aortic valve implantation, MMSE = mini-mental status examination, DW-MRI = diffusion weighted magnetic resonance imaging, ES = Edwards-SAPIEN, and MCV = Medtronic CoreValve.
aOnly 56 patients were able to undergo postprocedural imaging.