Figure 5.

Evaluation of serum creatine kinase level and renal and hepatic toxicity in the blood test at the end-point of 2 weeks after the last of nine systemic injections of 6 mg/kg 10-vPMO cocktail at 2-week intervals.Blood biochemical tests were performed for serum creatine kinase (CK), blood urea nitrogen (BUN), creatinine (Cre), total bilirubin (T-bil), and γ-glutamyl transpeptidase (γ-GTP) in wild-type (WT), nontreated (NT), and treated mdx52 mice (n = 4 in WT, n = 6 in NT and n = 4 in treated group). Data are presented as mean ± SE.