Table 1. Data on sputum smear results, Diabetes mellitus, and OSP results.

Subject pair	Xpert Positive Cases1					Matched healthy controls
	Sputum Smear Results	DM2	OSP3, Sample A	OSP, Sample B	OSP, Sample C	OSP, Sample A	OSP, Sample B	OSP, Sample C
1	+		Negative*	+*	+	Negative	Negative*	Negative
2	ND4		Negative*	+	+	Negative	Negative	Negative
3	Negative	+	Negative*	Negative*	Negative*	Negative	Negative	Negative
4	Negative	+	Negative*	Negative*	Negative*	Negative	Negative	Negative
5	Negative		+	+	+	Negative	Negative	Negative
6	Negative	+	+*	Negative*	+*	Negative*	Negative	Negative*
7	+++		+	+	+	Negative	Negative	Negative
8	+++		+	+	+	Negative	Negative	Negative
9	+++		+	+	+	Negative	Negative	Negative
10	+		+	+	Negative*	Negative	Negative	Negative
11	+++		+	+	+	Negative	Negative	Negative
12	++		+*	+	Negative*	Negative*	Negative	Negative
13	Negative		Negative*	+	+	Negative	Negative	Negative
14	ND	+	+	+	+	Negative	Negative	Negative
15	Negative		Negative*	+	+	Negative	Negative	Negative
16	+++		+*	+*	+*	Negative*	Negative*	Negative*
17	Negative		Negative*	+*	+	Negative	Negative*	Negative
18	ND		+	Negative*	+	Negative	Negative	Negative
19	+++		+	+	+	Negative	Negative	Negative
20	++		Negative*	+	+	Negative	Negative	Negative

¹All 20 case subjects were positive by GeneXpert testing and clinical assessment, and were subsequently treated for tuberculosis.

²DM, Diabetes mellitus. Cases 3, 4, 6, and 14 were in treatment for DM. Other cases were presumed DM-negative.

³For OSP, results of partial volume analysis are shown except values marked by asterisk (*), which are the full volume analysis conducted after partial results were negative. Negative results had Cq > 45.

⁴ND, not determined.