Table 2. Hematopoietic colonies derived from either untreated, cocaine, SR1 block, or cocaine and SR1 block exposed CD34 + cells that had been isolated from fetal liver. Values are the Mean and SEM. E, erythroid, M, macrophage, G, granulocyte, GM, mixed granulocyte-macrophage colonies.
| E | P value | M | P value | G | P value | GM | P value | |
|---|---|---|---|---|---|---|---|---|
| Donor 1 | 12.67 +/− 3.712 | 13.67 +/− 2.333 | 14.33 +/− 2.906 | 17.33 +/− 6.360 | ||||
| Cocaine | 0.0 +/− 0.0 | 0.027 | 11.33 +/− 2.603 | 0.541 | 0.0 +/− 0.0 | 0.0079 | 0.0 +/− 0.0 | 0.0527 |
| S1R Block | 11.67 +/− 1.453 | 0.8143 | 9.333 +/− 2.963 | 0.3416 | 12.00 +/− 2.517 | 0.5766 | 20.33 +/− 3.180 | 0.6948 |
| Both | 14.33 +/− 2.728 | 0.7358 | 13.33 +/− 2.603 | 0.9286 | 13.00 +/− 2.082 | 0.7281 | 15.67 +/− 2.404 | 0.8184 |
| Donor 2 | 10 +/− 2.887 | 13.00 +/− 2.646 | 13.33 +/− 2.603 | 15.33 +/− 3.756 | ||||
| Cocaine | 0.0 +/− 0.0 | 0.0257 | 12.00 +/− 3.606 | 0.834 | 0.0 +/− 0.0 | 0.0069 | 0.0 +/− 0.0 | 0.015 |
| S1R Block | 8.333 +/− 2.333 | 0.6767 | 14.00 +/− 3.215 | 0.822 | 10.00 +/− 3.125 | 0.4655 | 15.33 +/− 0.8819 | 0.9999 |
| Both | 8.333 +/− 2.028 | 0.6612 | 12.00 +/− 3.215 | 0.822 | 13.00 +/− 2.309 | 0.9283 | 16.00 +/− 3.606 | 0.9043 |
| Donor 3 | 9.00 +/− 2.887 | 14.00 +/− 3.215 | 14.67 +/− 3.180 | 14.33 +/− 2.603 | ||||
| Cocaine | 0.0 +/− 0.0 | 0.0356 | 11.00 +/− 3.606 | 0.5682 | 0.0 +/− 0.0 | 0.0099 | 0.0 +/− 0.0 | 0.0053 |
| S1R Block | 10.00 +/− 3.215 | 0.8283 | 14.33 +/− 4.055 | 0.8722 | 13.33 +/− 2.906 | 0.7724 | 14.00 +/− 3.786 | 0.9456 |
| Both | 7.333 +/− 2.028 | 0.6612 | 11.67 +/− 3.383 | 0.6433 | 13.33 +/− 4.096 | 0.8098 | 14.00 +/− 1.555 | 0.8662 |