Table 3. Genomic island (GI)-like regions identified in the LAC-4 chromosome.
| Region | Coordinates [CDS] | Length (kb) | G + C%a | Features |
|---|---|---|---|---|
| GI1 | 120,830–133,655 [ABLAC_01100–01230] | 12.8 | 42 | Novel composite transposon Tn6250 (formed by ISAba1 elements) encompassing entire island containing IS1006, partial ISVsa3, streptomycin and sulphonamide resistance genes, conjugal transfer functions TraA and TraD |
| GI2 | 547,857–581,621 [ABLAC_05290–05570] | 33.7 | 38 | Novel IS elements (ISAba26) flanking a 15-gene copper resistance cluster; another novel IS element (ISAba25); integrase |
| GI3 | 788,377–800,975 [ABLAC_07480–07600] | 12.6 | 43 | Novel IS elements (ISAba25); RND-type multidrug efflux pump proteins AdeI, AdeJ and AdeK and a partial ISAba1. |
| GI4 | 940,403–951,920 [ABLAC_08880–08980] | 11.5 | 40 | ISAba25; alpha/beta hydrolase superfamily; a gene encoding for ComEC-like protein; enzymes for biosynthesis of lipoproteins; purine biosynthesis enzymes |
| GI5 | 1,229,550–1,257,942 [ABLAC_11500–11860] | 28.4 | 40 | Insertion site: Arg tRNA gene (ABLAC_t00580); phage proteins |
| GI6 | 1,571,326–1,611,225 [ABLAC_14900–15460] | 39.9 | 39 | Two ISAba13 elements; mostly phage proteins |
| GI7 | 1,730,338–1,741,047 [ABLAC_16600–16720] | 10.7 | 35 | Integrase; phage proteins |
| GI8 | 1,941,480–1,993,076 [ABLAC_18640–19030] | 51.6 | 39 | Insertion site: Ser tRNA gene (ABLAC_t00260); ISAba13 and ISAba25; phage proteins |
| GI9 | 2,963,891–2,993,411 [ABLAC_28350–28700] | 29.5 | 36 | Mostly phage protein; ISAba13, ISAba125, ISAba25, ISAba26 |
| GI10 | 3,028,724–3,058,412 [ABLAC_29030–29480] | 29.7 | 35 | Insertion site: tmRNA gene (ABLAC_t00730); phage proteins; ISAba13 |
| GI11 | 3,367,720–3,386,189 [ABLAC_32320–32540] | 18.5 | 40 | ISAba26; gstB, frmA and frmB genes; Genes similar to the plasmid p3ABAYE and pABTJ2 are found |
| GI12 | 3,852,499–3,882,676 [ABLAC_36850–37160] | 33.4 | 35 | The K locus, which consists of genes encoding enzymes involved in biosynthesis of capsular polysaccharides, including two series of enzymes responsible for biosynthesis of α-L-frucosamine and α-8-epi-legionaminic acid, two sugars of the surface polysaccharide repeating units; six ORFs of unknown function which are unique for LAC-4 among completely sequenced A. baumannii genomes. |
aThe G + C content of the LAC-4 chromosome is 39%.