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Methanol consumption (filled symbols) and 13CO2 formation, reported as the 13CO2/total CO2 ratio (open symbols) of C. glutamicum Ptuf-Bm(mdh-act) Ptuf-Bs(hps-phi) (■) and C. glutamicum pVWEx2 pEKEx2 (●) during cultivation in CGXII defined medium supplemented with 55 mM glucose and 120 mM 13C-labeled methanol in bioreactors. Two independent experiments were performed, and mean values are shown.
