Figure 6.

Timing and similarity of co-infection affects success of both the resident and co-infecting strain. The percent of simulations that last longer than 50 days when varying similarity of co-infecting genotypes among VS antigens—no overlap (a), 25% overlap (b), 50% overlap (c), 75% overlap (d) and 100% overlap (e). Overlap refers to the percentage of VS antigens that are identical between genotypes. The co-infecting strain (red line) is favoured over the resident strain (blue line) at lower similarity and early during an infection. Parameters used are standard values in table 1 with only variation in the switching connections and switching rates. Without co-infection nearly 80% of genotypes lead to infections of over 50 days (black line).