Table 1. Electrophysiological signatures of ASD and their potential for biomarker use.
Biomarker | Simple to Implement | Sensitive | Specific | Scale | Responsive to Treatment | Biological Basis | Predictive |
M50/100 Latency Delay | √ | √ | √ | √ | √ (pre-clinical) | √ (hypothesized) | untested |
MMF/N | √ | √ | to RDoC domain but not clinical label | √ | untested | less clear | untested |
Gamma Band Dysfunction | √ | √ | to RDoC domains, but not clinical label | √ | √ | √ | √ |