Table 1.
Summary of the reaction rates in response to intracellular and extracellular [Au(CN)2]−
| Location | Residue | Intra. [Au(CN)2]−, ATP, /M/s | Intra. [Au(CN)2]−, no ATP, /M/s | Extra. [Au(CN)2]−, forskolin, /M/s | Extra. [Au(CN)2]−, forskolin, with G1349D, /M/s |
| Outside | R334C | 189 ± 39 | — | 403 ± 20 | 537 ± 56 |
| K335C | — | — | 56 ± 9 | 1,809 ± 201 | |
| F337C | 437 ± 49 | — | 20 ± 3 | 32 ± 6 | |
| T338C | 752 ± 59 | — | 1,135 ± 166 | 118 ± 18 | |
| Inside | I344C | 32 ± 5 | 37 ± 4 | — | — |
| N1148C | 437 ± 66 | 2,089 ± 130 | — | — |
Residues located extracellularly (extra.) to the predicted narrow region are in italics, and residues in roman type represent positions intracellularly (intra.) to this region. The reaction rates are presented as mean ± SEM (n = 4–14).