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. 2015 Feb 26;2(2):e77. doi: 10.1212/NXI.0000000000000077

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© 2015 American Academy of Neurology

This is an open access article distributed under the terms of the Creative Commons Attribution-Noncommercial No Derivative 3.0 License, which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially.

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(A) Intracellular cytokine analysis for interleukin (IL)-10 following 48-hour stimulation with rCD40L and LPS (BFA, PMA, and ionomycin for the last 5 hours). Representative plots in a healthy control and a patient with muscle-specific tyrosine kinase (MuSK) myasthenia gravis (MG) are gated on CD19⁺ cells, and the numbers in the plots represent the frequency of IL-10–positive events. (B) Comparison of the mean percentages of B10 cells in healthy controls and patients with MuSK MG (n = 13; p = 0.013). (C) Comparison of B10 cell percentages and B cell–activating factor (BAFF) levels in patients with MuSK MG (p = 0.041).