Table 1.
Principal reports in morphological abnormality in templal cortex, limbic and frontal cortex in schizophrena
Are | Findings | Reporter | |
---|---|---|---|
Temporal lobe Limbic | quantity | Volume loss in hippocampus, amygdala, parahippocampus | Bogerts, 19855, 19906; Altshuler, 19907 |
Enlargement in left ventlicle | Borgerts, 19855; Heckers, 19908, 19919 | ||
Volume loss in hippocampal formation | Colter, 198710; Heckers, 19919 | ||
Neuronal loss in hippocampal formation | Benes, 199811; Casanova, 199012 | ||
quality | Cytoarchitectic abnormality in hippocampus, cinglate | Arnold, 1991a13; Conrad, 199114 | |
Distribution abnormality in NADPH-d positive neuron | Akbarian, 1993b15 | ||
Frontal lobe | quantity | Neuronal loss (number/density) | Benes, 198616; Arnold, 199517 |
Decreased density of internal neurons | Benes, 199118 | ||
Increased vertical axsons in anterior cingrate cortex | Benes, 1987b19 | ||
Narrowing cell body & decreased density in anterior cingrate | Chana, 200320 | ||
quality | Abnormal array of neurons in layer II | Benes, 198616, 1987a21 | |
Distribution abnormality in NADPH-d positive neuron | Akbarian, 1993a22 | ||
(Modified from Harrison, 199923) |
Also, some findings were reported in cerebellum, brainstem, nucleus basalis, thalamus, corpus callosum and another area of cerebral cortex.