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. 2015 Mar 2;6:56. doi: 10.3389/fgene.2015.00056

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Copyright © 2015 Gillette, Miller-Crews, Skinner and Crews.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression in the medial preoptic area (mPOA). Relative gene expression of (A) Steroid hormone receptor Ar, which shows a decrease of expression due to ancestral exposure. (B) Peptide receptor Lepr shows an effect of vinclozolin treatment, an effect driven by the large increase in expression in C-S animals. (C,D) Steroid synthesis enzyme Cyp19a1 (aromatase) and steroid hormone receptor Esr1 are both up-regulated by CRS. (E) Peptide receptor Mc5r shows an effect of vinclozolin exposure. Expression in C-S animals is also increased. Lines connecting group bars signify a significant post hoc pair-wise test.