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Plasma Renin Concentration and Activity (Mean±SEM)
| ctl‐dTGR | VDd‐dTGR | P Value | |
|---|---|---|---|
| PRC (sheep substrate) ng Ang I/(mL per h) | 16.45±7.3 | 26.58±12.5 | 0.05 |
| PRC (rat substrate) ng Ang I/(mL per h) | 11.47±3.4 | 23.29±9.1 | 0.01 |
| PRA ng Ang I/(mL per h) | 35.79±35.81 | 54.22±38.8 | 0.34 |
| Ang I ng/mL | 4.98±1.6 | 8.58±2.5 | 0.01 |
Ang I indicates angiotensin I; ctl‐dTGR, controls double‐transgenic rats; PRA, plasma renin activity; PRC, plasma renin concentration; VDd, vitamin D‐depleted.
