Table 7.
Multivariable Cox Proportional Hazards Analysis for Cardiovascular Events in 393 CAD Patients
| Variables | Coding | Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | HR | 95% CI | P Value | ||
| Age | Per 1 year | 1.01 | 0.99 to 1.04 | 0.30 | 1.01 | 0.99 to 1.04 | 0.29 | 1.01 | 0.99 to 1.04 | 0.36 |
| Sex | Male (vs female) | 0.83 | 0.53 to 1.30 | 0.42 | 0.84 | 0.54 to 1.31 | 0.44 | 0.72 | 0.46 to 1.13 | 0.15 |
| BMI | Per 1 kg/m2 | — | — | — | — | — | — | — | — | — |
| Hypertension | Yes (vs no) | — | — | — | — | — | — | — | — | — |
| DM | Yes (vs no) | 1.81 | 1.12 to 2.90 | 0.01 | 1.84 | 1.15 to 2.92 | 0.01 | 1.58 | 1.00 to 2.52 | 0.05 |
| Dyslipidemia | Yes (vs no) | — | — | — | — | — | — | — | — | — |
| Current smoking | Yes (vs no) | — | — | — | — | — | — | — | — | — |
| Family history of CAD | Yes (vs no) | — | — | — | — | — | — | — | — | — |
| LVEF | Per 1% | — | — | — | — | — | — | — | — | — |
| Ln‐DROM | Per 1 ln‐DROM | 10.0 | 2.41 to 41.7 | 0.002 | 10.8 | 2.76 to 42.4 | 0.001 | — | — | — |
| Ln‐Hs‐CRP | Per 1 ln‐Hs‐CRP | 1.04 | 0.86 to 1.25 | 0.71 | — | — | — | 1.13 | 0.94 to 1.36 | 0.18 |
| Ln‐BNP | Per 1 ln‐BNP | 1.30 | 1.06 to 1.60 | 0.01 | 1.31 | 1.07 to 1.60 | 0.01 | 1.32 | 1.08 to 1.62 | 0.006 |
| Ln‐hs‐troponin T | Per 1 ln‐Hs‐troponin T | — | — | — | — | — | — | — | — | — |
| eGFR | Per 1 mL/min per 1.73 m2 | — | — | — | — | — | — | — | — | — |
| Complex plaques | Complex (vs simple) | 1.73 | 1.10 to 2.72 | 0.02 | 1.73 | 1.12 to 2.72 | 0.02 | 1.85 | 1.18 to 2.91 | 0.007 |
| MVD | MVD (vs SVD) | 1.08 | 0.65 to 1.77 | 0.77 | 1.08 | 0.66 to 1.77 | 0.77 | 1.26 | 0.77 to 2.05 | 0.35 |
Model 1: significant factors in crude Cox proportional hazards analysis. Model 2: significant factors in crude Cox proportional hazards analysis without ln‐hs‐CRP. Model 3: significant factors in crude Cox proportional hazards analysis without ln‐DROM. BMI indicates body mass index; BNP, B‐type natriuretic peptide; CAD, coronary artery disease; DM, diabetes mellitus; DROM, derivatives of reactive oxygen metabolites; eGFR, estimated glomerular filtration rate; HR, hazard ratio; Hs‐CRP, high‐sensitivity C‐reactive protein; Hs‐troponin T, high‐sensitivity troponin T; LVEF, left ventricular ejection fraction; MVD, multiple‐vessel‐disease; SVD, single‐vessel‐disease.