Table 2.
Demographic and clinical characteristics of ADPKD study population by CKD disease stage
| Setting of care | CKD Stage 1 (n=316) |
CKD Stage 2 (n=404) |
CKD Stage 3 (n=860) |
CKD Stage 4 (n=611) |
CKD Stage 5 (n=842) |
Dialysis (n=586) |
Post-transplant (n=615) |
P-value |
|---|---|---|---|---|---|---|---|---|
| Hospitalizations | ||||||||
| n (%) | 51 (16.1) | 49 (12.1) | 150 (17.4) | 141 (23.1) | 360 (42.8) | 274 (46.8) | 252 (41.0) | <0.0001 |
| Mean (SD) | 0.22 (0.56) | 0.18 (0.59) | 0.19 (0.57) | 0.24 (0.66) | 0.31 (0.72) | 0.59 (0.84) | 0.70 (0.97) | <0.0001 |
| Total length of stay, mean (SD) (days)a | 5.69 (7.17) | 7.22 (11.39) | 7.66 (12.09) | 6.17 (10.55) | 7.55 (8.95) | 8.71 (11.43) | 8.56 (13.67) | 0.3253 |
| Hospital outpatient visits | ||||||||
| n (%) | 218 (69.0) | 284 (70.3) | 668 (77.7) | 504 (82.5) | 779 (92.5) | 556 (94.9) | 575 (93.5) | <0.0001 |
| Mean (SD) | 3.05 (5.23) | 2.60 (4.07) | 3.50 (4.73) | 5.39 (6.89) | 11.87 (16.59) | 13.82 (19.51) | 10.10 (12.22) | <0.0001 |
| Outpatient physician office visits | ||||||||
| n (%) | 308 (97.5) | 391 (96.8) | 835 (97.1) | 601 (98.4) | 793 (94.2) | 540 (92.2) | 574 (93.3) | <0.0001 |
| Mean (SD) | 7.03 (6.19) | 6.68 (6.04) | 7.48 (6.84) | 8.87 (6.71) | 9.16 (8.44) | 8.45 (10.18) | 8.97 (8.32) | <0.0001 |
| Outpatient prescription claims | ||||||||
| n (%) | 281 (88.9) | 379 (93.8) | 824 (95.8) | 581 (95.1) | 803 (95.4) | 553 (94.4) | 579 (94.1) | 0.0003 |
| Mean (SD) | 12.22 (12.08) | 14.68 (13.98) | 18.03 (14.82) | 19.50 (14.35) | 23.31 (16.29) | 23.09 (16.48) | 27.76 (18.60) | <0.0001 |
| ESRD facility | ||||||||
| Visited an ESRD facility, n (%) | 15 (4.7) | 2 (0.5) | 15 (1.7) | 39 (6.4) | 292 (34.7) | 321 (54.8) | 26 (4.2) | <0.0001 |
| Mean (SD) ESRD visits (n) | 1.21 (8.32) | 0.19 (3.43) | 0.46 (6.44) | 1.48 (8.38) | 10.38 (26.07) | 21.22 (38.97) | 1.14 (9.18) | <0.0001 |
Note:
a
Mean number of hospitalizations and mean lengths of hospitalization stay were calculated only among patients with at least one visit.
Abbreviations: ADPKD, autosomal dominant polycystic kidney disease; CKD, chronic kidney disease; ESRD, end-stage renal disease; SD, standard deviation.