Table 2.
Characteristics and month | CSA patients, mean ± SD | TAC patients, mean ± SD | P-value |
---|---|---|---|
eGFR, mL/minute/1.73 m2 | |||
Baseline | 82.13±30.72 | 70.75±39.77 | ns |
6 | 60.89±24.14* | 55.46±23.10* | ns |
12 | 59.48±23.18* | 60.91±25.17* | ns |
24 | 61.28±25.04* | 57.61±24.92* | ns |
Serum creatinine, mg/dL | |||
Baseline | 1.12±0.53 | 1.47±0.94 | 0.0066 |
6 | 1.47±0.59* | 1.65±1.01† | ns |
12 | 1.46±0.47* | 1.48±0.83† | ns |
24 | 1.42±0.44* | 1.67±1.30† | ns |
Serum sodium, mmol/L | |||
Baseline | 136.65±3.86 | 137.72±3.43 | ns |
6 | 138.82±3.75* | 137.99±3.90† | ns |
12 | 138.84±2.94* | 139.31±2.94* | ns |
24 | 138.60±3.47* | 139.18±2.80* | ns |
Serum potassium, mmol/L | |||
Baseline | 4.23±0.50 | 4.27±0.54 | ns |
6 | 4.05±0.42* | 4.05±0.46* | ns |
12 | 4.28±0.41† | 4.34±0.53† | ns |
24 | 4.28±0.36† | 4.36±0.54† | ns |
Notes:
P<0.05 vs baseline, statistically significant
P<0.05 vs baseline, ns.
Abbreviations: CSA, cyclosporine A; SD, standard deviation; TAC, tacrolimus; eGFR, estimated glomerular filtration rate; ns, not statistically significant.