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. 2015 Feb 23;10:407–414. doi: 10.2147/COPD.S76047

Table 2.

Comparison of characteristics for subjects with a confirmed diagnosis of COPD (ie, post-bronchodilator FEV1/FVC <0.70) with and without bronchodilator reversibility

Reversibility (n=60) No reversibility (n=627) P-value
Sex, male 35 (58%) 334 (52%) 0.452
Age 63 (10.0) 63 (10.5) 0.407
BMI 26 (5.7) 26 (5.0) 0.531
Pack-years 42 (23.5) 40 (23.2) 0.380
Symptoms
 Cough 33 (55%) 468 (75%) 0.001
 Dyspnea 43 (72%) 355 (57%) 0.024
 Wheezing 16 (27%) 167 (27%) 0.996
 Sputum 25 (42%) 256 (41%) 0.900
 Recurrent RTI 10 (17%) 78 (12%) 0.349
MRC 2.2 (0.8) 2.0 (0.8) 0.152
Spirometry
 FEV1 screeninga 1.7 (0.6) 1.9 (0.7) 0.014
 FEV1% predictedb 58 (13.4) 68 (19.6) <0.001

Notes: Data are given as the mean (standard deviation) or number (%) of subjects; a positive reversibility test defined as ΔFEV1 >0.200 L and 12% of pre-bronchodilator FEV1 level after administration of bronchodilator

a

FEV1 at initial screening spirometry

b

FEV1 % predicted.

Abbreviations: BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; MRC, Medical Research Council dyspnea scale; RTI, respiratory tract infection.