Table 3. Baseline and endpoint serum lipid values for a subset of 50 COMIT participants across the high oleic canola, high oleic canola and DHA blend, and corn and safflower blend treatments.

	High-oleic canola oil		DHA-high-oleic canola oil		Corn/safflower oil		Diet effect

	Start	End	Start	End	Start	End	Start	End
TC	5.44 ± 0.01	4.91± 0.01^*	5.40 ± 0.01	4.95 ± 0.01^*	5.57 ± 0.01	4.87 ± 0.01^*	p=0.1452	p=0.3643
LDL-C	3.40 ± 0.10	2.92 ± 0.09^a ^*	3.32 ± 0.10	3.10 ± 0.09^b ^*	3.51 ± 0.10	2.90 ± 0.09^a ^*	p=0.0775	p=0.0007
HDL-C	1.22 ± 0.04	1.16 ± 0.04^a ^*	1.21 ± 0.04	1.25 ± 0.04^b ^*	1.26 ± 0.04	1.20 ± 0.04^a ^*	p=0.0209	p=0.0010
TG	1.81 ± 0.18	1.80 ± 0.17^a	1.92 ± 0.18	1.31 ± 0.17^b ^*	1.76 ± 0.18	1.68 ± 0.17^a	p=0.0674	p<0.0001

TC= total cholesterol, LDL-C =low density lipoprotein cholesterol, HDL-C = high density lipoprotein cholesterol, TG= triglycerides. All values in mmol/L. The values are given as least squares mean ± SE for 50 individuals. Mixed-effects repeated-measures analysis of variance with treatment, age, sex as fixed effect, center as a random effect, and the measures for each participant repeated by period were used for the data analysis with Tukey-Kramer adjustment for multiple comparisons.

^abc

Mean values with different superscript letters across diets denote significant differences at p<0.05.

denotes significant change from start value of same diet.