Skip to main content
. Author manuscript; available in PMC: 2015 Mar 2.
Published in final edited form as: Microvasc Res. 2014 Jul 30;95:76–81. doi: 10.1016/j.mvr.2014.07.009

Fig. 3.

Fig. 3

IGFBP-3 overexpression inhibited TNFR1 and TNFR2 expression in high glucose medium and the TNFR2 inhibition was dependent on LRP1. A. Western Blot of TNFR1 levels in REC transfected with IGFBP-3 NB plasmid DNA or LRP1 siRNA for 24 h in medium containing normal glucose (NG-5 mM) or high glucose (HG-25 mM) medium. B. Western Blot of TNFR2 levels in REC transfected with IGFBP-3 NB plasmid DNA or LRP1 siRNA for 24 h in medium containing normal glucose (NG-5 mM) or high glucose (HG-25 mM) medium.*P < 0.05 vs. NG control plasmid DNA transfection. #P < 0.05 vs. HG control plasmid DNA transfection. $P < 0.05 vs. HG IGFBP-3 NB plasmid. N = 3.