Table 2. Associations of baseline variables with serum bilirubin and rs6742078.
Serum bilirubin | rs6742078 | |||
---|---|---|---|---|
Variables | Standardized β coefficients (95%CI) | P value | Standardized β coefficients (95%CI) | P value |
Age | 0.012 (−0.021 to 0.046) | 0.46 | 0.013 (−0.021 to 0.046) | 0.46 |
Female sex | −0.215 (−0.245 to −0.181) | <0.001 | 0.001 (−0.033 to 0.034) | 0.97 |
Smoking | −0.015 (−0.050 to 0.017) | 0.35 | 0.003 (−0.030 to 0.037) | 0.87 |
Alcohol use | 0.049 (0.015 to 0.082) | 0.01 | 0.02 (−0.013 to 0.054) | 0.24 |
Family history of diabetes | −0.057 (−0.093 to −0.026) | 0.001 | 0.018 (−0.016 to 0.051) | 0.30 |
Prior history of CVD | −0.026 (−0.060 to 0.007) | 0.13 | 0.026 (−0.003 to 0.064) | 0.14 |
BMI | −0.119 (−0.152 to −0.085) | <0.001 | 0.006 (−0.028 to 0.039) | 0.74 |
Waist circumference | −0.025 (−0.059 to 0.008) | 0.14 | −0.002 (−0.036 to 0.032) | 0.91 |
Systolic blood pressure | 0.039 (0.00 to 0.072) | 0.02 | −0.007 (−0.040 to 0.027) | 0.70 |
Diastolic blood pressure | 0.040 (0.003 to 0.070) | 0.03 | −0.003 (−0.036 to 0.031) | 0.88 |
Hypertension | 0.013 (−0.020 to 0.046) | 0.44 | −0.017 (−0.051 to 0.016) | 0.32 |
Fasting glucose | −0.021 (−0.055 to 0.013) | 0.22 | 0.025 (−0.009 to 0.058) | 0.15 |
HDL cholesterol | 0.025 (−0.009 to 0.058) | 0.15 | −0.006 (−0.039 to 0.027) | 0.73 |
Triglycerides | −0.116 (−0.148 to −0.082) | <0.001 | 0.001 (−0.033 to 0.034) | 0.97 |
Fasting insulin | −0.106 (−0.140 to −0.072) | <0.001 | −0.002 (−0.036 to 0.032) | 0.87 |
AST | 0.145 (0.112 to 0.178) | <0.001 | −0.003 (−0.036 to 0.030) | 0.85 |
ALT | 0.082 (0.049 to 0.115) | <0.001 | 0.021 (−0.013 to 0.054) | 0.22 |
GGT | 0.030 (−0.007 to 0.060) | 0.12 | 0.010 (−0.023 to 0.043) | 0.55 |
Albumin | 0.247 (0.212 to 0.282) | <0.001 | −0.014 (−0.052 to 0.023) | 0.44 |
ALP | −0.022 (−0.054 to 0.013) | 0.24 | 0.022 (−0.015 to 0.060) | 0.23 |
hs-CRP | −0.115 (−0.147 to −0.080) | <0.001 | −0.010 (−0.044 to 0.023) | 0.55 |
UAE | −0.031 (−0.066 to 0.002) | 0.07 | 0.006 (−0.027 to 0.040) | 0.72 |
BMI: body mass index, HDL: high-density lipoprotein, GGT: gamma-glutamyltransferase, ALT: alanine aminotransferase, AST: aspartate aminotransferase, ALP: Alkaline phosphatase, hs-CRP: high sensitivity C-reactive protein and UAE: urine albumin excretion.