Table 2.
N=35 | RTL* | hTERT$ | TA# | |||||
---|---|---|---|---|---|---|---|---|
Characteristic | n | % | mean (SD) | p-value | mean (SD) | p-value | mean (SD) | p-value |
IPSS** score | ||||||||
Low+int-1 | 21 | 60 | 1.08 (0.10) | 14.42 (1.53) | 14.43 (1.31) | |||
Int-2+high | 14 | 40 | 1.36 (0.13) | 0.10 | 10.45 (1.97) | 0.12 | 10.96 (1.14) | 0.06 |
Cytogenetics | ||||||||
Normal | 15 | 43 | 1.07 (0.08) | 12.72 (2.00) | 12.59 (1.36) | |||
Abnormal | 20 | 57 | 1.36 (0.12) | 0.07 | 13.38 (1.71) | 0.80 | 13.62 (1.35) | 0.60 |
WHO## MDS subtype | ||||||||
MDSU+RARS | 6 | 17 | 1.45 (0.23) | 17.39 (4.95) | 13.05 (2.85) | |||
RCMD | 15 | 43 | 1.11 (0.09) | 12.58 (1.72) | 13.74 (1.53) | |||
RAEB1+RAEB2 | 14 | 40 | 1.25 (1.46) | 0.33 | 11.76 (1.62) | 0.31 | 12.55 (1.35) | 0.85 |
RTL=Relative telomere length;
hTERT= Human telomerase reverse transcriptase
TA=Telomerase activity;
IPSS=International Prognostic Scoring System;
WHO=World Health Organization