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. 2015 Mar 2;10(3):e0117224. doi: 10.1371/journal.pone.0117224

Table 4. Multiple linear regression analysis of predictors of the proportion of ACL-MSCs at passage 0 in overall patients and in the ACL reconstruction and total knee arthroplasty groups.

Dependentvariables Independent Variables Unstandardized coefficients Standardized coefficients
B SE (B) β P-value VIF
ACL-MSC P0 (%) of overall subjects Age 0.018 0.056 0.046 0.750 1.423
Gender (male) -2.762 2.317 -0.167 0.238 1.374
Body mass index 0.172 0.272 0.080 0.529 1.119
ACL-MSC P0 (%) of ACL reconstruction group Age -0.301 0.101 -0.445 0.065 1.034
Gender (male) -2.358 2.546 -0.144 0.361 1.120
Body mass index 0.402 0.343 0.178 0.251 1.085
ACL-MSC P0 (%) of TKA group Age 0.175 0.291 0.107 0.552 1.007
Gender (male) 7.135 4.671 0.276 0.137 1.043
Body mass index -0.352 0.385 -0.166 0.368 1.050

P, passage; MSC, mesenchymal stem cell; ACL, anterior cruciate ligament

B, unstandardized coefficients; SE (B), standard error of B; β standardized coefficients

The adjusted R2 for ACL-MSC proportion at passage 0 were 0.053 in all patients, 0.228 in the ACL reconstruction group, and 0.095 in the TKA group.