Table 5. Upregulation and downregulation of genes in TKA-MSCs compared with ACL-MSCs.
| Ref Seq NM | Gene Symbol | Fold change | P-value | DEFINITION |
|---|---|---|---|---|
| NM_198097.1 | C7orf28B | 3.848 | 0.00001 | Chromosome 7 open reading frame 28B (C7orf28B) |
| NR_001564.1 | XIST | 3.706 | 0.00000 | X (inactive)-specific transcript (non-protein coding) (XIST) |
| NM_005807.3 | PRG4 | 3.398 | 0.00930 | Proteoglycan 4 (PRG4), transcript variant A |
| NM_002462.2 | MX1 | 3.113 | 0.00276 | Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1) |
| NM_003248.3 | THBS4 | 2.594 | 0.00403 | Thrombospondin 4 (THBS4) |
| NM_001008.3 | RPS4Y1 | -18.121 | 0.00000 | Ribosomal protein S4, Y-linked 1 (RPS4Y1) |
| NM_002781.2 | PSG5 | -7.116 | 0.00000 | Pregnancy specific beta-1-glycoprotein 5 (PSG5) |
| NM_004681.2 | EIF1AY | -4.658 | 0.00000 | Eukaryotic translation initiation factor 1A, Y-linked (EIF1AY) |
| NM_002781.2 | PSG5 | -3.866 | 0.00222 | Pregnancy specific beta-1-glycoprotein 5 (PSG5) |
| NM_000211.1 | ITGB2 | -3.653 | 0.00403 | Integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) (ITGB2) |
| NM_000211.2 | ITGB2 | -3.105 | 0.03896 | Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2) |
Positive values represent upregulation. Negative values represent downregulation.