Skip to main content
. Author manuscript; available in PMC: 2015 Mar 3.
Published in final edited form as: J Alzheimers Dis. 2014;41(2):535–549. doi: 10.3233/JAD-132789

Figure 3. Soluble and insoluble Aβ is not affected by Aβ immunization and LXR agonist treatment.

Figure 3

Soluble Aβ was extracted from cortexes and hippocampi by TBS followed by extraction of insoluble using formic acid, and Aβ was evaluated by ELISA. On panel A is shown insoluble Aβ40 and Aβ42 and on panel B, soluble Aβ40 and Aβ42. C, The level of Aβ oligomers was measured in soluble fraction using dimer-specific ELISA as described in the methods. For all panels, difference between the means were analyzed by one-way ANOVA and showed no significant change and two-way ANOVA demonstrated no interaction and no significant main effects of LXR or anti- Aβ treatments. N=6–14 male and female mice per group.