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. Author manuscript; available in PMC: 2015 Mar 3.
Published in final edited form as: Exp Neurol. 2010 Dec 22;228(1):80–90. doi: 10.1016/j.expneurol.2010.12.011

Fig. 1.

Fig. 1

Circadian dysfunction is a common feature of mouse models of HD. Mice were placed individually in cages with running wheels, and locomotor activity was recorded under different lighting conditions. Each horizontal row represents an activity record for a 24-hr day. Successive days are plotted from top to bottom. The grey shading represents darkness. Mice were initially held in LD (12:12) and then released into DD. Panels show examples of the wheel-running activity recorded from WT (A), BACHD (B) , R6/2 CAG 250 (C), R6/2 CAG 140 (D), and CAG 140 (E). The mice were all 2-3 mo of age. See Table 1 for detailed analysis.