Table 3.
Longitudinal associations between statins and decline in PASE (n= 3,039).
| Age & Site Adjusted | Fully Adjusted1 | |||||
|---|---|---|---|---|---|---|
| Annual decline in PASE (95% CI) |
Estimated diff. in decline (95% CI)2 |
p- value3 |
Annual decline in PASE (95% CI) |
Estimated diff. in decline (95% CI)2 |
p-value3 | |
| Nonuser | 2.8 (2.3, 3.2) | ref | 2.5 (2.0, 3.0) | ref | ||
| Prevalent User |
2.9 (2.2, 3.6) | 0.1 (−0.7, 0.9) | 0.02 | 2.8 (2.1, 3.5) | 0.3 (−0.5, 1.1) | 0.07 |
| New User | 3.9 (3.3, 4.5) | 1.1 (0.3, 1.9) | 3.4 (2.8, 4.0) | 0.9 (0.1, 1.7) | ||
Abbreviations: CI, confidence intervals; Diff, difference; PASE, Physical Activity Scale for the Elderly; ref, reference group
1
Model controlled for the following variables: age, site, and baseline total cholesterol (fixed-in-time); myocardial infarction, stroke, hypertension, diabetes, perceived health, and body mass index (time-varying)
2
Estimate of the statin use × time interaction with nonusers as a reference group
3
Type III p-value for the statin use × time interaction