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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Diabetologia. 2015 Jan 7;58(3):633–642. doi: 10.1007/s00125-014-3470-y

Fig. 8.

Fig. 8

TNFα-mediated apoptosis and cell cycle gene regulation is FOXO1 dependent. hBMSCs were transfected with control (scrambled siRNA) or FOXO1 siRNA, followed by TNFα treatment for 72 h. Quantitative RT-PCR was carried out and ribosomal protein L32 mRNA was used to normalise the mRNA values. (a–d) Quantification of relative mRNA fold changes for: (a) CASP8; (b) CASP9; (c) P21; and (d) P27. *p<0.05 vs all groups