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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Cortex. 2014 Oct 16;64:55–67. doi: 10.1016/j.cortex.2014.10.002

Figure 2.

Figure 2

T-score maps of brain areas for which volume loss was associated with higher levels of happiness behavior in patients with FTD (n= 96) when controlling for age, sex, CDR-SB, diagnosis, study wave, field strength, handedness, and total intracranial volume. Smaller volume in a cluster (Max T= 3.98) that included left ventrolateral and orbitofrontal cortex; left anterior insula, striatum, rostromedial prefrontal cortex, and superior frontal gyrus; and bilateral gyrus rectus was associated with higher happiness behavior after correction for Type 1 error (pFWE<.05). Color bar represents T-scores (hot= pFWE<.05 according to study-specific permutation analysis, T> 2.63). Results for all analyses are overlaid on the warping template from DARTEL.