Table 1. Characteristics of studies included in the meta-analysis.

	First author	Year	Ethnicities	Genotyping method	Number of Cases and controls	Genotype distribution(case/control)			HWE
−1195G/A						GG	GA	AA
	Gharib,A16		2014	Egyptian	PCR	120/130	17/31	60/66	43/33	0.859
	Mohamed,F10		2014	Egyptian	PCR	75/125	12/40	49/22	14/63.	<0.001
	Chang,W,S17		2012	Chinese	PCR	298/300	70/74	144/145	84/81	0.570
	Fan,X,J14		2011	Chinese	PCR	780/780	204/205	390/381	186/194	0.523
	Akkiz,H18		2011	Turkish	PCR	129/129	2/2	36/32	91/95	0.708
	Liu,L,F13		2010	Chinese	PCR	210/420	31/101	110/216	69/103	0.557
	Xu,D,K16		2008	Chinese	PCR	270/540	52/119	125/287	93/134	0.138
−765G/C							GG	GC	CC
	Gharib,A16		2014	Egyptian	PCR	120/130	86/85	30/39	4/6	0.579
	He,J15		2012	Chinese	PCR	300/900	223/772	67/118	10/10	0.027
	Chang,W,S17		2012	Chinese	PCR	298/298	262/250	36/48	0/0	0.139
	Akkiz,H18		2011	Turkish	PCR	129/129	79/75	46/39	4/15	0.009
	Xu,D,K16		2008	Chinese	PCR	270/540	233/515	37/25	0/0	0.582
+8473T/C							TT	TC	CC
	Chang,W,S17		2012	Chinese	PCR	298/298	195/201	103/97	0/0	<0.001
	Fan,X,J14		2011	Chinese	PCR	780/780	509/497	235/258	36/25	0.222
	Akkiz,H18		2011	Turkish	PCR	129/129	65/58	56/62	8/9	0.161