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. 2015 Mar 2;10(3):e0118251. doi: 10.1371/journal.pone.0118251

Table 2. The meta-analysis results of association between Cyclooxygenase-2 polymorphisms and hepatocellular carcinoma risk.

SNPs Contrast model OR(95%CL) PA Test for heterogeneity publication bias (Egger’s test)
I2 (%) P t p
−1195G/A
A vs G 1.118(0.947–1.319) 0.186 65.1 0.009 0.12 0.909
GA vs GG 1.558(1.055–2.303) 0.026 72.5 0.001 1.31 0.247
AA vs GG 1.466(1.194–1.801) 0.000 31.5 0.187 −0.26 0.808
GA+AA vs GG 1.356(1.148–1.602) 0.000 23.4 0.251 2.10 0.090
GG+GA vs AA 0.982(0.692–1.392) 0.917 82.1 0.000 0.71 0.508
+8473T/C
C vs T 0.986(0.863–1.126) 0.833 0.0 0.682 0.02 0.989
TC vs TT 0.927(0.752–1.144) 0.480 0.0 0.471 −0.34 0.790
TC+CC vs TT 0.934(0.760–1.147) 0.513 0.0 0.497 −0.37 0.775
TC+TT vs CC 0.764(0.482–1.210) 0.252 0.0 0.374 - -
−765G/C
C vs G 1.223(0.700–2.136) 0.480 41.38 0.000 −0.16 0.882
GC vs GG 1.323(0.764–2.290) 0.317 85.2 0.000 −0.67 0.549
CC vs GG 0.863(0.164–4.530) 0.861 13.56 0.001 −1.39 0.398
GC+CC vs GG 1.269(0.710–2.274) 0.423 87.7 0.000 −0.85 0.460
GG+GC vs CC 1.195(0.244–5.844) 0.826 12.63 0.002 1.18 0.447